Endocrine Abstracts

The treatment of hypothyroidism is straightforward,replacing with orally L-thyroxine(LT4).However,some factors including malabsorption,pancreas and liver disorders,drug interactions,etc.,may impair the absorption of LT4,and cause therapy failures.In these circumstances,high doses of different oral formulae or parenterally given LT4 may be a solution. Here,we present a case of primary hypothyroidism,resistant to high doses of oral LT4 replacement but,responsive parenteral LT4 a...

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is also known as autoimmune polyendocrine syndrome type 1 (APS-1). We present a case of autoimmune polyendocrine syndrome type 1 with hypercalcaemia of adrenal insufficiency during the calcium treatment because of hypoparathyroidism.Case: A 20-year-old female patient was diagnosed with APS-1 in 2004. She applied to ER with the complaints of nausea and vomiting. Her laboratory finding...